(P03-037-24) Association Between Symptom Severity and Related Factors Among Individuals With Irritable Bowel Syndrome in Korea: A Cross-Sectional Study
Woori Na: No relevant financial relationship(s) with ineligible companies to disclose.
Objectives: Irritable Bowel Syndrome (IBS) presents with diverse symptomatology influenced by individual traits, necessitating a comprehensive understanding of contributing factors. This study aimed to delineate the features of IBS symptom severity in Korean patients, employing the Irritable Bowel Syndrome Severity Scoring System (IBS-SSS) and exploring associated factors.
Methods: Conducted through online surveys, the study recruited 239 Korean adults aged 20-64, adhering to ROME IV criteria. Survey domains encompassed demographics, IBS symptom severity assessed via the IBS-SSS, and dietary habits assessed using a Food Frequency Questionnaire (FFQ). Symptom severity was graded on a scale of 0 to 500, categorized as mild (75-174), moderate (175-299), or severe (≥300). Statistical analyses, including cross-analysis, ANOVA, and post-hoc tests, were performed using SPSS version 26.0, with a significance level set at p< 0.05.
Results: Results revealed that among the participants, 100 (41.9%) had mild symptoms, 104 (43.5%) had moderate symptoms, and 35 (14.6%) had severe symptoms. Factors showing significant differences according to symptom severity included stress (p < 0.001), stool form (p=0.049), and experience of nutrition education or dietary therapy (p=0.001). Although overall FODMAPs intake did not exhibit significant differences, age-stratified analysis revealed variations in fructan intake according to symptom severity. Notably, among individuals aged 30-49, fructan intake was 3.33±2.36 g (mild)(a), 4.80±3.75 g (moderate)(b), and 4.53±2.76 g (severe)(ab), respectively (p < 0.03).
Conclusions: These findings underscore the multifactorial nature of symptom severity in IBS and emphasize the need for personalized management strategies considering factors such as stress, nutrition education, and dietary intake.
Funding Sources: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea Government (MSIP) (No. NRF-2020R1A2C1014177).