(P15-010-24) Coffee Intake and Adiposity in Postmenopausal Women With Overweight and Obesity: Secondary Analysis of a Randomized Controlled Trial

Objectives: To assess the association between coffee intake and adiposity in generally healthy postmenopausal women with overweight and obesity.

Methods: This study was a cross-sectional, secondary analysis of baseline data of participants in the Minnesota Green Tea Trial. Coffee intake was assessed using the validated Diet History Questionnaire I. Total body fat and trunk fat percentages were measured using dual x-ray absorptiometry. General linear models were used to assess the association between coffee intake and total body fat and trunk fat percentages using an unadjusted model and a model adjusted for age, education level, alcohol intake, physical activity, energy intake, and added sugar intake. P for trends were also calculated to assess the dose-response effect of increasing coffee intake.

Results: Data from 116 postmenopausal participants with overweight and obesity were available. The sample consisted of non-Hispanic women who were mostly White (95.7%) with mean values for age, BMI, total body fat percentage, and trunk fat percentage of 60.4 years, 27.1 kg/m², 42.0%, and 44.0%, respectively. The most frequent coffee intake was 2-3 cups of coffee daily (38.8%). In the unadjusted model, compared to participants who drank no coffee, participants who drank ≥4 cups daily had significantly lower total body fat percentage (β= -3.47; 95% confidence interval [CI]= -6.21, -0.73; P trend=0.014) and trunk fat percentage (β= -3.85; 95% CI= -7.49, -0.21; P trend=0.038). However, statistical significance for both outcomes was lost after adjustment for relevant covariates.

Conclusions: Coffee intake was not associated with adiposity in postmenopausal women with overweight and obesity. Research studies on coffee intake and adiposity have been heterogeneous in design and yielded conflicting results; thus, additional research is needed to better understand the association between coffee intake and adiposity.

Funding Sources: The parent trial was sponsored by the National Institutes of Health/National Cancer Institute (Grant #R01CA127236).