(P04-027-24) Effects of a Dietary Supplement on Hydration and Circulation in Body

Objectives: Hydration status of the body influences many factors within the body. This includes the circulatory, lymphatic, and detoxification systems. Healthy lifestyle choices and dietary supplements can impact hydration. The objective of this study was to deliver a flavored mix-in powder supplement (SUP) that contained 150mg grape seed extract, 100mg vitamin C, 5g Acacia gum fiber, and 225mg electrolytes (Na, K, Mg, and Ca) and determine the effects on circulation, skin hydration, and subjective self-perception responses.

Methods: 31 healthy subjects between the age of 25-65y consumed SUP mixed into 8oz water for 30d. Another group of subjects (n=31) also used a hand-held, non-invasive body device--BD with hydrating serum along with supplement. Assessments were collected at timepoints: baseline, after 1 treatment, week 1, and week 4. Questionnaires were completed regarding skin attributes, hydration, wellness, etc. Assessments were made of circulation (arm and leg) using Laser Doppler (LD) readings and skin hydration (arm and leg) using a corneometer and trans-epidermal water loss (TEWL) using Tewameter. P-value < 0.05 compared to baseline and between groups were considered statistically significant.

Results: LD for both arm and leg were sig increased from baseline in the SUP group at all timepoints. Self-perception results in SUP group showed a sig improvement from baseline for outcomes such as feeling more hydrated, feeling like they had healthy circulation in their arms and legs, SUP helped them look and feel better, lifting mood and improved overall feelings of wellbeing, etc. Skin hydration using Corneometer and TEWL measurements in both arm and leg increased sig in group receiving SUP alone from baseline at all timepoints. The group using SUP and BD had sig increase in skin hydration over SUP group alone at all timepoints with greater skin hydration over time.

Conclusions: Subjects consuming the SUP experienced a sig improvement in circulation and skin hydration. Subjects consuming SUP and BD had even greater improvement in skin hydration. This demonstrates an inside out approach in that improved hydration in body results from using SUP and BD. Overall, this study demonstrates the SUP resulted in improved hydration and circulatory health and that combining SUP along with a BD can provide enhanced skin hydration benefits.

Funding Sources: NSE Products, Inc.